Leukocyte are not only important as first innate defense against pathogens but they also play a fundamental role in the progression of cardiovascular diseases.
Our aim is to characterize the interconnection between leukocyte and endothelial cells in order to modulate inflammatory responses as therapeutic approach in cardiovascular associated pathology such as diabetes. To achieve this goal, we investigate the role of microRNAs and exosomes in different in vivo and in vitro assays.