2024
Hasan, MZ; Claus, M; Krüger, N; Reusing, S; Gall, E; Bade-Döding, C; Braun, A; Watzl, C; Uhrberg, M; Walter, L. SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E expression. Emerg Microbes Infect. 2024 Dec;13(1):2361019. doi: 10.1080/22221751.2024.2361019.
Flury, P; Breidenbach, J; Krüger, N; Voget, R; Schäkel, L; Si, Y; Krasniqi, V; Calistri, S; Olfert, M; Sylvester, K; Rocha, C; Ditzinger, R; Rasch, A; Pöhlmann, S; Kronenberger, T; Poso, A; Rox, K; Laufer, SA; Müller, CE; Gütschow, M; Pillaiyar, T. Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. In: ACS Pharmacology & Translational Science. 2024, 7, 2, 493–514. DOI: 10.1021/acsptsci.3c00313.
Kaiser FK*, Hernandez MG*, Krüger N*, Englund E*, Du W, Mykytyn AZ, Raadsen MP, Lamers MM, Rodrigues Ianiski F, Shamorkina TM, Snijder J, Armando F, Beythien G, Ciurkiewicz M, Schreiner T, Gruber-Dujardin E, Bleyer M, Batura O, Erffmeier L, Hinkel R, Rocha C, Mirolo M, Drabek D, Bosch BJ, Emalfarb M, Valbuena N, Tchelet R, Baumgärtner W, Saloheimo M, Pöhlmann S, Grosveld F, Haagmans BL, Osterhaus ADME. Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models. In: Nat Commun. 2024 Mar 14;15(1):2319. DOI: 10.1038/s41467-024-46443-0.
2023
Krüger, N; Kronenberger, T; Xie, H; Rocha, C; Pöhlmann, S; Su, H; Xu, Y; Laufer, SA; Pillaiyar, T
Discovery of Polyphenolic Natural Products as SARS-CoV-2Mpro Inhibitors for COVID-19
In: Pharmaceuticals 2023,16(2), 190: doi: 10,3390/ph/16020190
Budhadev, D; Hooper, J; Rocha, C; Nehlmeier, I; Kempf, AM; Hoffmann, M; Krüger, N; Zhou, D; Pöhlmann, S; Guo, Y
Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein
In: JACS Au; 2023, 3(6):1755-1766, doi: 10.1021/jacsau.3c00163
Kaboudi, N; Krüger, N; Hamzeh-Mivehroud, M
Development of novel ligands against SARS-CoV-2 M pro enzyme: An in silico and in vitro study
In: Molecular Informatics, 2023 Aug 17:e2300120, doi: 10.1002/minf.202300120
Laliberté, A; Prelli Bozzo, C; Stahl-Hennig, C; Hunszinger, V; Joas, S; Sauermann, U; Roshani, B; Klippert, A; Daskalaki, M; Mätz-Rensing, K; Stolte-Leeb, N; Tharp, GK; Fuchs, D; Gupta, PM; Silvestri, G; Nelson, SA; Parodi, L; Giavedoni, L; Bosinger, SE; Sparrer, KMJ; Kirchhoff, F
Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIVmac239 in rhesus macaques.
In: iScience. 2023 Oct 26;26(12):108351. doi: 10.1016/j.isci.2023.108351.
Stab, V; Stahl-Hennig, C; Ensser, A; Richel, E; Fraedrich, K; Sauermann, U; Tippler, B; Klein, F; Burton, DR; Tenbusch, M; Überla, K
HIV-1 neutralizing antibodies provide sterilizing immunity by blocking infection of the first cells.
In: Cell Rep Med. 2023 Oct 17;4(10):101201. doi: 10.1016/j.xcrm.2023.101201.
Festag, J; Festag, MM; Asen, T; Wettengel, JM; Mück-Häusl, MA; Abdulhaqq, S; Stahl-Hennig, C; Sacha, JB; Burwitz, BJ; Protzer, U; Wisskirchen, K
Vector-Mediated Delivery of Human Major Histocompatibility Complex-I into Hepatocytes Enables Investigation of T Cell Receptor-Redirected Hepatitis B Virus-Specific T Cells in Mice, and in Macaque Cell Cultures.
In: Hum Gene Ther. 2023 Dec;34(23-24):1204-1218. doi: 10.1089/hum.2023.035.